Implicity has announced the results of a clinical study published in the Cardiovascular Digital Health Journal, reaffirming that its proprietary algorithm is highly effective at identifying patterns and classifying AF episodes into medically relevant events that require clinical action, the company says.
Researchers found that the algorithm significantly reduced the number of alerts related to transmissions by cardiac implantable electronic devices (CIEDs) in patients being remotely monitored for atrial fibrillation (AF) by filtering standard device notifications and automatically classifying episodes that meet the threshold for clinical relevance.
“For a patient with AF who is already anticoagulated, a single AF episode is not as important as established patterns or occurrences associated with arrhythmia progression and patient outcomes. This study proved Implicity’s algorithm can reduce AF alert fatigue by effectively detecting trends, both positive and negative, and categorizing events that require intervention or adjustments in treatment,” said Jagmeet P Singh (Harvard Medical School, Boston, USA).
The retrospective study analysed real-life data from more than 4,000 recipients of an Abbott, Biotronik, Boston Scientific, or Medtronic CIED who were being continuously monitored for AF.
Implicity compared the incidence of standard CIED-transmitted alerts from device manufacturers with the incidence of events detected after filtering by the algorithm. Results showed the algorithm broke down 67,883 AF burden-related alerts into 9,728 (14.3%) clinically relevant AF events, according to the European Society of Cardiology (ESC) classification. Notably, the median number of alerts per patient year decreased by 57.9%.
“Sending physicians only clinically-relevant alerts, based on the detection of distinct presentations of AF, can reduce the time electrophysiologists spend reviewing notifications that do not require action by several hours. This will increase the efficiency and quality of care of patients with AF, save time for the medical staff, and help promote the adoption of RPM—leading to more meaningful remote monitoring and ultimately better outcomes,” said Arnaud Rosier, electrophysiologist, CEO, and co-founder of Implicity.