Writing in Circulation: Cardiovascular Quality and Outcomes, David Ouyang (Stanford University, Falk Research Center, Palo Alto, USA) and others report that while the number of female first and senior authors of cardiovascular research papers has increased over the past...
BioCardia has announced its 510(k) submission for US FDA clearance of the Avance steerable introducer, which is designed for introducing various cardiovascular catheters into the heart, including via the left side of the heart through the interatrial septum. A...
Sixty years ago, the first pacemaker implant was made in Stockholm, Sweden (Senning & Elmqvist) on 8 October 1958. The patient had atrioventricular block with recurrent Adams-Stokes attacks. These were prevented by the implant—although, it only functioned for a...
The first patient has been treated in the TERMINATE AF trial (Medtronic). This is a multi-centre study evaluating two surgical ablation devices—the Cardioblate irrigated RF (IRF) system and the CryoFlex surgical ablation system—for the treatment of non-paroxysmal (persistent or...
Biosense Webster has enrolled and treated the first patient in its STELLAR US investigational device exemption (IDE) study. The study will evaluate the safety and effectiveness of Heliostar multi-electrode radiofrequency balloon ablation vatheter in treating symptomatic drug refractory recurrent...
CardioFocus has completed enrolment in a trial to evaluate its next-generation HeartLight X3 endoscopic ablation system. According to a press release, a total of 60 patients have been treated in this pivotal confirmatory trial with a one-month follow up....
A post-hoc analysis of the ICD Sports Registry—which has already indicated that many patients with implantable cardioverter defibrillators (ICD) can safely participate in vigorous or competitive sports—shows that shocks are not infrequent in young ICD patients who play competitive...
Data presented at the 2018 American Heart Association (AHA) scientific session scientific sessions (10–12 November, Chicago, USA) indicate that the use of alert-based computerised-decision support significantly increases the rate of anticoagulation prescription among patients who are hospitalised with atrial...
Quentin Fischer (Department of Cardiology, Quebec Heart and Lung Institute, Laval University, Quebec City, Canada) and others report in Circulation: Cardiovascular Interventions that patients with pre-existing left bundle branch block (LBBB) have a significantly increased risk of requiring permanent...
Abbott has announced the start of LESS-VT—the first US clinical trial to evaluate the safety and effectiveness of ablation treatment for patients with monomorphic ventricular tachycardia. The LESS-VT study, which is currently enrolling patients, will evaluate the safety and...

Tim Betts

For Tim Betts, a career in medicine was a natural choice. After graduating he knew he wanted to be a cardiologist and, with a fascination for arrhythmias and ECGs, he became hooked on electrophysiology. His research is focused on...
Data from an open-label, pilot randomised trial (TRED-HF) indicate that if heart failure treatment is withdrawn in patients with recovered dilated cardiomyopathy, many will relapse and require treatment to be reinitiated. These findings suggest that until predictors of relapse...
The US FDA has announced plans to modernise its 510(k) clearance programme for approving medical devices for the US market. Data show that about 20% of current 510(k) devices are approved on trials that compare novel devices to predicate...
During AF Association Global AF Aware Week, Biosense Webster EMEA has published a report that uncovers the growing burden of atrial fibrillation (AF) on patients, caregivers and healthcare systems across Europe. The new report is calling for greater awareness and...
New harmonised outcome measures for atrial fibrillation (AF) have been published in HeartRhythm. The work was funded by the Agency for Healthcare Research and Quality (AHRQ) through an interagency agreement with the Office of the Secretary Patient Centered Outcomes...
Positive 12-month data have been presented for the roll-in cohort of the pivotal CardiAMP Heart Failure Trial studying the investigational CardiAMP Cell Therapy System (BioCardia) in adult patients experiencing heart failure following a heart attack. The results were presented...
The VASCADE MVP (Cardiva Medical), a vascular closure system designed specifically for multi-access venous closure following electrophysiology procedures such as arrhythmia ablation, met its endpoints compared to manual compression in a pivotal clinical study. The AMBULATE study is the...
People who experience migraine with visual aura may have an increased risk of atrial fibrillation, according to a study published in the online issue of Neurology, the medical journal of the American Academy of Neurology. Migraine with visual aura is...
An international study, led by researchers from the Intermountain Medical Center Heart Institute in Salt Lake City, found that a smartphone app (AliveCor) to monitor heart activity and determine if someone is having an ST-segment elevation myocardial infarction (STEMI) has...
Maisense, a start-up company specialising in stroke prevention, has recently introduced an AI-based solution that can screen stroke through early detection of atrial fibrillation (AF), that will also be presented at MEDICA (12–15 November, Düssledorf, Germany). Patients with AF have...
EPIX Therapeutics, a medical device company that designs and manufactures a catheter-based system for the treatment of patients with atrial fibrillation (AF), has announced achievement of the enrolment goal of the DIAMOND-AF study, a global FDA-approved IDE pivotal study...
Cardiva Medical, an innovator in the field of vascular closure, has announced that new data from the randomised AMBULATE study will be presented in a late-breaking session on new trials in cardiovascular care at Scientific Sessions 2018, the annual...
The American College of Cardiology, the American Heart Association and the Heart Rhythm Society have released a guideline for the evaluation and treatment of patients with bradycardia, or a slow heartbeat, and cardiac conduction disorders. In the guideline, bradycardia is...
Researchers at Stanford University's School of Medicine have completed enrolment of a large-scale study using the Apple Watch to determine whether a wearable technology can identify atrial fibrillation. The study rationale and design, published in the American Heart Journal,...
Cardiac Insight, Inc., a developer of wearable cardiac biosensors and clinical diagnostic software systems featuring proprietary automated data analysis algorithms, has announced its partnership with VivoSense, a company focused on integration and specialised analysis of wearable sensor data for...
The HeartMate 3 left ventricular assist device has received US FDA approval as a destination therapy for people living with advanced heart failure. With the approval, physicians can now offer the HeartMate 3 system to patients not eligible for...
A new meta-analysis of patients undergoing percutaneous closure of patent foramen ovale (PFO) after cryptogenic shock supports previous studies that indicate PFO closure is associated with an increased risk of atrial fibrillation. However, it also shows that device-related atrial...
Cardialen, a medical device company developing a low-energy implantable defibrillation therapy designed to more gently restore normal heart rhythm, has announced the closing of a US$17 million Series B investment led by RiverVest Venture Partners, along with Qiming Venture Partners,...
Medtronic has issued a software update "to address a safety risk caused by cybersecurity vulnerabilities" in 34,000 of their cardiac implantable electronic devices (CIEDs), the US FDA write in a safety communication to healthcare professionals. Following a review of...
CathVision, an early stage medical device company developing an advanced cardiac electrophysiology recording system, CUBE, has announced that the company received ISO 13485:2016 certification for Medical Device and Quality Management Systems from Lloyd's Register. This ISO certification indicates that the...
Adagio Medical, the developer of the iCLAS technology—the company's ultra-low temperature intelligent continuous lesion ablation system for the treatment of cardiac arrhythmias—announces that the first patients were successfully treated with its new One Shot+ cryoablation catheter. The new catheter...
Johnson & Johnson have announced that Biosense Webster has received approval from the US Food and Drug Administration (FDA) for its VISITAG SURPOINT External Processing Unit and enrolment has begun in its post-market approval study. The VISITAG SURPOINT Module calculates...
New guidelines for the management of cardiovascular diseases during pregnancy, including upgraded recommendations of catheter ablation and risk-dependent action plans, were presented by Carina Blomström-Lundqvist, Uppsala University, Uppsala, Sweden, at the European Society of Cardiology Congress (ESC; 25–29 August,...
LivaNova has announced the first successful implantation of the Vitaria system in a patient enrolled in the Autonomic regulation therapy to enhance myocardial function and reduce progression of heart failure with reduced ejection fraction (ANTHEM-HFrEF) pivotal study. The study...
AtaCor Medical has announced that it has completed a US$8.8M Series A financing. Co-led by Boston-based Broadview Ventures and Israel-based aMoon Ventures, the financing also includes participation from a corporate partner. The investment will support the continued development of...
This article has been sponsored by Abbott Case description A 31 year-old female with tricuspid atresia and normally related great vessels who underwent an atriopulmonary Fontan (total cavopulmonary anastomosis) at two years of age and a subsequent Fontan revision to a...
Amit N Vora (Duke University Medical Center/the Duke Clinical Research Institute, Durham, USA) and others report in in JACC: Cardiovascular Interventions that patients who develop atrial fibrillation after undergoing transcatheter aortic valve implantation (TAVI) have a higher risk of...
Transvenous lead extraction in cardiac resynchronisation therapy (CRT) patients is not associated with increased 30-day mortality vs. non-CRT patients. The study found that age, renal impairment and sepsis were independent predictors of 30-day mortality and sepsis was the main...
Four out of ten patients with atrial fibrillation but no history of stroke or transient ischaemic attack have previously unknown brain damage, according to the first results of the Swiss Atrial Fibrillation Cohort Study (Swiss-AF) presented at European Society...
Atricure have announced that the enrolment of the full cohort of 153 patients in the CONVERGE IDE clinical trial has been completed. CONVERGE IDE is the first prospective, randomised study comparing the Convergent approach to endocardial catheter ablation in persistent...
New findings from the CRYO4PERSISTENT AF clinical trial demonstrate improved quality of life, reduced symptoms from abnormal heart rhythms, and low incidence of reinterventions and repeat ablation procedures. The study evaluated patients with symptomatic persistent atrial fibrillation (AF) treated...
Biotronik is now the exclusive US distributor for InfoBionic's MoMe Kardia external cardiac diagnostic monitor, it has announced in a press release. The device benefits patients suspected of experiencing cardiac arrhythmias and is designed to increase early detection and...
Thomas S Gilhofer (University Heart Center, Department of Cardiology, University Hospital Zurich, Zurich, Switzerland) and others report in Structural Heart that a combined procedure involving both transcatheter aortic valve implantation (TAVI) and left atrial appendage closure is a feasible...
At the 2018 European Society of Cardiology (ESC) Congress (25–29 August, Munich, Germany), British Heart Foundation (BHF) announced the “Big Beat Challenge”—an £30m award that seeks to bring together world-leading researchers and innovators to identify and solve any of...
At the 2018 European Society of Cardiology (ESC) Congress (25–29 August, Munich, Germany), Siemens Healthineers launched Magnetom Sola Cardiovascular Edition—a 1.5 Tesla magnetic resonance imaging (MRI) scanner that is specifically designed for cardiovascular examinations. A press release reports that...
WeHealth, by Servier, has launched Cardioskin—a connected solution that is designed to function as an ambulatory wearable 15-lead ECG—at the 2018 European Society of Cardiology Congress (25–29 August, Munich, Germany). A press release reports that Cardioskin is composed of...
Royal Philips has introduced the EPIQ CVx cardiovascular ultrasound system. Built on the powerful EPIQ ultrasound platform, EPIQ CVx is specifically designed to increase diagnostic confidence and simplify workflow for clinicians, giving them more time to interact with their...
More than 100,000 people have been trained in hands-only cardiopulmonary resuscitation (CPR) since the American Heart Association (AHA) launched its hands-only CPR training kiosk programme in 2016. As part of the programme, that is supported by Anthem Foundation in...
A feasibility study of a novel left atrial appendage device (Ultraseal, Cardia) indicates that the device is associated with a high rate of procedural success and a fast learning curve. It also suggests that the device has an extremely...
BioSig Technologies have announced that the Company has received 510(k) clearance for its first product, PURE EP System, from the US Food and Drug Administration (FDA). The non-invasive PURE EP System is a computerised system intended for acquiring, digitising, amplifying,...
Milestone Pharmaceuticals, a clinical-stage cardiovascular company, announced that the first patient has been randomised in its phase 3 clinical study of etripamil. Etripamil is a new investigational, rapid-onset, short-acting calcium channel blocker administered intranasally by the patient designed to...
Medtronic plc have announced the start of a pilot study of its investigational extravascular implantable cardioverter defibrillator (EV ICD) system, in which a lead is placed outside of the heart and veins to deliver lifesaving defibrillation and antitachycardia pacing...
A new study, published in JAMA Network Open, indicates that patients with atrial flutter have a lower incidence of stroke than patients with atrial fibrillation who have the same CHA2DS2-VASc score. Given current European guidelines advise that patients with...
VisCardia has announced the first implant of its VisONE implantable system for heart failure, and the commencement of its VisONE Heart Failure pilot study in Ukraine. According to a press release, the VisONE implantable system delivers VisCardia’s proprietary asymptomatic...
How to best combine optimal screening and diagnosis for atrial fibrillation (AF) has long been a challenge. At European Heart Rhythm Association Congress (EHRA; 18–20 March 2018, Barcelona, Spain) Jens Eckstein (University of Basel, Basel, Switzerland) presented the case...
A study looking at patients undergoing lead extraction found that they were more likely to survive superior vena cava tears when treatment included the Bridge occlusion balloon. Lead author, Roger Carrillo (University of Miami, Miami, USA) concluded that when...
Cyber security has become a hot topic in recent years. Leslie Saxon writes in Cardiac Rhythm News about the cybersecurity risks for implantable cardiac devices. In the past year, the US FDA and a division of Homeland Security that responds...
The American Heart Association (Association) and Laerdal Medical (Laerdal) are furthering their decades-long alliance to deliver a new standard of resuscitation quality and patient care centred on CPR competence. Attendees representing 30 of the nation’s largest health care systems...
MEDICALgorithmics and US subsidiary Medi-Lynx Cardiac Monitoring L.L.C., have announced that the US Food and Drug Administration (FDA) has granted 510(k) clearance for the PocketECG Cardiac Rehabilitation System (CRS), a new mobile cardiac rehabilitation system designed to provide high-quality...
A phase 3 trial of Zoll Medical’s LifeVest has missed its primary endpoint. The study found that people who started using the wearable defibrillator the week after they had a heart attack did not experience a statistically significant reduction...
Boston Scientific has signed an agreement to acquire Claret Medical, which developed and commercialised the Sentinel cerebral embolic protection system. The device is used to protect the brain during certain interventional procedures, predominately in patients undergoing transcatheter aortic valve...
Medtronic has announced the first enrolments in a new clinical trial evaluating the ECG (electrocardiography) Belt Research System (ECG Belt) as a diagnostic tool for optimising cardiac resynchronisation therapy (CRT) for patients with heart failure. The first patient enrolled...
The link between cardiac diseases and stroke is well known and reported. Wolfram Döhner writes in Cardiac Rhythm News about the needs for interdisciplinary thinking and collaboration. Stroke is a leading cause of death and the main cause of physical...
His bundle pacing was successful in 92% of patients and the primary endpoint of death, heart failure hospitalisation or upgrade to biventricular pacing was significantly reduced in the His bundle pacing group. Right ventricular pacing is associated with heart...
Symptomatic atrial fibrillation (AF) patients with previous failed catheter ablation or structural changes associated with higher recurrence of AF could benefit from thoracoscopic ablation and left atrial appendage excision. The thoracoscopic approach was associated with higher initial rates of...
Bardy Diagnostics has announced that it has raised additional growth capital from its existing equity investors, including SV Health Investors ("SVHI"), Health Enterprise Partners, and Ascension Ventures. The growth capital will be used to expand BardyDx's sales force and...
The mHealth Screening To Prevent Strokes (mSToPS) randomised clinical trial showed that home-based wearable electrocardiogram (ECG) sensor patch monitoring, compared with delayed monitoring, resulted in a higher rate of atrial fibrillation (AF) diagnosis after four months. Wearing an ECG patch...
Differences between men and women mean that outcomes after cardiac events can differ between the sexes. Cecilia Linde writes in Cardiac Rhythm News about a new consensus document that looks to address these issues. There is an increasing awareness that...
A press release has announced US Food and Drug Administration (FDA) labeling expansion for the Medtronic SelectSecure MRI SureScan Model 3830 cardiac pacing lead to include stimulation of the bundle of His. It is the only pacing lead on...
A press release reports that the CALYPSO programme will receive 14 million euros to develop CorWave Neptune—a new type of cardiac support designed to improve the management of patients with severe heart failure—as part of the Programme d’Investissements d’Avenir(PIA)...
Medtronic has received United States Food and Drug Administration (FDA) approval for a less-invasive implant approach of its HVAD System, a left ventricular assist device (LVAD) for patients with advanced heart failure. The HVAD System is the smallest commercially...
Black people who survive cardiac arrest during hospitalisation have lower odds of long-term survival compared with similar white survivors, according to new research published in Circulation.  Half the difference in one-year survival rates, however, remained unexplained. Nearly one-third of the racial...
CorWave has announced that it has obtained patent no. US 9,968,720 B2 on May 15, 2018 from the US Patent and Trademark Office. Titled “Implantable pump system having an undulating membrane,” according to a press release, this patent describes...
Research finds use of smaller, self-contained devices reduced complications for up to 18 months compared with conventional designs The findings of the research, led by Ohio-based Cleveland Clinic, appeared in the journal Heart Rhythm. The study compared patient outcomes for...
CorWave obtained patent no. US 9,968,720 B2 on May 15, 2018 from the United States Patent and Trademark Office. Titled “Implantable pump system having an undulating membrane,” the patent describes the application of CorWave’s technology for blood pumping in a...
This article was sponsored by Abbott. Left ventricular assist devices (LVAD) are mechanical pumps that are implanted inside a person's chest to help their weakened heart ventricle pump blood throughout the body. The mechanical device supports the left heart chamber...
As part of its plan to expand it atrial fibrillation ablation therapy offering, Boston Scientific Corporation has announced a definitive agreement to acquire Cryterion Medical, a privately-held company developing a single-shot cryoablation platform for the treatment of atrial fibrillation...
Investigators at Children's Hospital Los Angeles and the University of Southern California, Los Angeles, USA, have demonstrated the feasibility of implanting a micropacemaker system in the pericardial sac surrounding the heart — a breakthrough that may open up new cardiac pacing...
By Hannah Woolley Findings from the Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease (COMPASS) trial suggest that the combination of low-dose rivaroxaban and aspirin significantly lowers the incidence of both major adverse cardiovascular...
The annual census of UK consultants and higher speciality trainees—Focus on Physicians 2017–18—indicates that more than half of all consultants and two thirds of trainees reported frequent gaps in trainees’ rotas, with one in five respondents saying these are...
By Hannah Woolley In a multivariate analysis including both BRUISE CONTROL 1 and BRUISE CONTROL 2 patients and adjusted for antiplatelet use, there was no difference in clinically significant haematoma between direct oral anticoagulants (DOACs) and warfarin. Oral anticoagulant use is...
By Hannah Woolley Longer dwell times are related to higher rates of complication during lead extraction. There have been various studies looking at the risk factors for transvenous lead extraction but there is limited knowledge about extraction of leads that...
Patients with scar-related ventricular tachycardia (VT) do not often achieve a cure. Jason S Bradfield and Kalyanam Shivkumar write in Cardiac Rhythm News about how to tackle this issue. Success with medical therapy or catheter ablation may involve long periods...
HeartSciences has announced that it has been highlighted as a “Start-Up to Watch” in the June 8, 2018 issue of the MedTech Strategist. The article titled “Heartsciences: artificial intelligence improves frontline risk stratification for heart diseases” discusses HeartSciences’ role...
Wearable cardioverter defibrillators – vest-like devices that deliver electric shocks to interrupt a dangerous heart rhythm – may be a safe and effective alternative to surgically implanted devices in children with ventricular heart rhythm disorders that put them at risk for...
Catheter ablation for atrial fibrillation (AF) produced no significant improvement in death, disabling stroke, serious bleeding, or cardiac arrest but did reduce death or cardiovascular hospitalization and recurrent AF in the Catheter Ablation versus Antiarrhythmic Drug Therapy (CABANA) trial,...
Published in the heart journal Europace, the researchers found that a 10% loss in weight along with management of associated risk factors, can reverse the progression of the disease. They studied 355 overweight or obese people who lost varying amounts...
New guidance regarding the selection and evaluation of wearable devices for use in regulatory trials and to support labelling claims has been published in the journal Value of Health. The report, Selection of and Evidentiary Considerations for Wearable Devices and...
The US Food and Drug Administration (FDA) released the following two draft guidance documents: These guidance documents provide industry and FDA staff with recommendations on the least burdensome means of assessing the performance of catheters, guidewires, and delivery systems submitted...
The first-in-human phase I trial will take place in Australia for Verseon’s PROAC (PRecision Oral AntiCoagulant) VE-1902, which has successfully completed regulatory toxicology studies and was well-tolerated in 28-day repeat dosing. PROACs are a novel class of anticoagulants that show...
A new study has found that the more alcohol you drink, the higher your heart rate gets. These finding were presented at European Heart Rhythm Association Congress (EHRA; 18–20 March 2018, Barcelona, Spain). The Munich Beer Related Electrocardiogram Workup (MunichBREW)...
The trials found that ultralow temperature cryoablation is feasible and shows excellent safety and efficacy. The clinical outcomes for flutter ablation show a 94% success rate at three months. Ultralow temperature ablation uses near-critical nitrogen. The catheter operates at the...
The algorithm (Kardiaband, AliveCor) for atrial fibrillation (AF) detection, when supported by physician review can accurately differentiate AF from sinus rhythm (SR). This technology can help screen patients prior to elective cardioversion and avoid unnecessary procedures. One hundred patients were...
The American Heart Association has announced research grants totalling more than US$28 million to the scientific teams that will create a new research network focused on understanding the causes of atrial fibrillation (AFib). The new knowledge they discover will...
BIOTRONIK have announced the opening of its Education and Innovation Centre in Ebisu, Tokyo, Japan. The centre will provide the latest educational programs and services for medical professionals and respond to the needs of medical practitioners through efficient information...
The American College of Cardiology (ACC), Heart Rhythm Society (HRS), North American Society for Cardiovascular Imaging (NASCI), Society for Cardiovascular Angiography and Interventions (SCAI), and the Society for Computed Tomography (SCCT) have published, in the Journal of the American...
Zenicor Medical Systems AB has been selected as sole supplier for a screening programme in the UK for atrial fibrillation. The screening programme is the world’s largest randomised controlled trial to discover whether screening systematically for atrial fibrillation, a...
Royal Philips has announced that it has signed an agreement to acquire EPD Solutions. EPD’s cardiac imaging and navigation system helps electrophysiologists navigate the heart by generating a detailed 3D image of the cardiac anatomy, while also pinpointing the...
The United States Food and Drug Administration (FDA) has classified Medtronic recent voluntary urgent field action related to the HeartWare HVAD System unexpected power source switching as a Class I recall. Class I recalls describe situations where there is...
The total procedure-related complications after surgical minimally invasive pulmonary vein isolations (MIPI) were higher; this was mainly due to more major complications. During a two-year follow-up there were three transient ischaemic attacks or cerebrovascular accidents after MIPI compared to...
Researchers will use a European network of 90,000 patients, including 20,000 DNA samples, to look at different approaches for prevention and treatment of sudden cardiac arrest for men and women. Sudden cardiac arrest is the consequence of the heart rhythm...
Apixaban and warfarin are equally safe during catheter ablation of atrial fibrillation, according to results of the AXAFA-AFNET 5 (Anticoagulation using the direct factor Xa inhibitor apixaban during Atrial Fibrillation catheter Ablation: Comparison to vitamin K antagonist therapy) (German...
The Copenhagen City Heart Study set out to investigate whether left atrial (LA) functional measures predict atrial fibrillation (AF) in the general population. They found that LA functional measures predict AF in the general population and can provide prognostic...
The first systematic evaluation of coagulation point-of-care testing in edoxaban treated patients has been carried out. The results were presented by Florian Härtig, University of Tuebingen, Germany, at the International Stroke Conference (ISC; 24–26 January 2018, Los Angeles, USA) Currently...
The interim results of the REAFFIRM (Randomised Evaluation of Atrial Fibrillation treatment with Focal Impulse and Rotor Modulation guided procedures) trial showed there was no statistically significant difference in outcomes between the treatment and control arms. These results were...
Octreotide therapy has the potential to offer atrial fibrillation (AF) patients with arteriovenous malformations (AVM) related gastrointestinal (GI) bleeding another treatment option. It is a safe way to reinitiate oral anticoagulants (OACs) by bringing down the risk of repeat...
One-year results from the Dielectric Unravveling of RAdiofrequency ABLation Effectiveness (DURABLE-I) clinical trial have shown that the KODEX (Navix International Limited) system help to improve effectiveness by detecting gaps in real time during the index ablation procedure. The results...
The results of the WATCH AF trial, the world’s first international, prospective and double-blinded clinical trial (ClinicalTrials.gov ID: NCT02956343) evaluating the accuracy of a smartwatch to detect atrial fibrillation were announced at the European Heart Rhythm Association Congress. (EHRA...

Dhanunjaya Lakkireddy

Dhanunjaya Lakkireddy is executive medical director at The Kansas City Heart Rhythm Institute at HCA Midwest Health, Kansas, USA. He holds the title Professor of Medicine, is board certified in Cardiology and Electrophysiology and is a renowned electrophysiologist. He...

Luigi Di Biase

Luigi Di Biase is a prominent electrophysiologist, section head of Electrophysiology, director of Arrhythmia Services, and professor of Medicine (Cardiology) at the Albert Einstein College of Medicine, New York, USA. In addition, he serves as senior researcher at the...
Highlights: Apixaban is a safe alternative to warfarin during catheter ablation of atrial fibrillation and may have a positive effect on cognitive function Stroke prevention drugs may help reduce dementia risk for atrial fibrillation patients, consensus document finds Leslie...
Highlights: Apixaban is a safe alternative to warfarin during catheter ablation of atrial fibrillation and may have a positive effect on cognitive function Stroke prevention drugs may help reduce dementia risk for atrial fibrillation patients, consensus document finds Leslie...
Boston Scientific Europe has announced the launch of the HeartLogic Heart Failure Diagnostic in Europe. With this launch, the first and only diagnostic tool that enables proactive heart failure (HF) care is now available for patients in select countries...
iRhythm Technologies has announced results of a study which utilised Zio by iRhythm, an extended continuous cardiac monitoring system, to provide a comprehensive picture of the burden of atrial fibrillation (AF) in patients. Utilising this data in combination with...
Results from a research study demonstrating the feasibility of a novel approach to delivering pacing and defibrillation therapy in which a lead is placed under the sternum (breastbone), outside of the heart and veins have been announced. Data from...
Study results show that the AdaptivCRT algorithm is associated with improved patient survival. The real-world, prospective registry of 1,835 patients, use of the AdaptivCRT algorithm was associated with a 31% relative reduction in all-cause mortality compared to conventional cardiac...
Results from an analysis of the LATITUDE database which evaluated the successful reduction of inappropriate shocks using the SMART Pass sensing filter in patients implanted with the EMBLEM Subcutaneous Implantable Defibrillator (S-ICD) System have been announced. The real-world data...
The AngelMed Guardian System is an implantable cardiac monitor intended to detect and alert patients of a potential heart attack. The Guardian System consists of three components: The Implantable Medical Device (IMD), which monitors the heart's electrical activity (electrograms)...
Two-year results show rivaroxaban was associated with reduced stroke and systemic embolism versus warfarin, without altering risk of major bleeding. The study evaluated efficacy and safety of rivaroxaban, apixaban and dabigatran each versus warfarin. The Janssen Pharmaceutical Companies of Johnson...
The US FDA has issued a class I recall due to a malfunction in the device’s outflow graft assembly that may cause the outflow graft to twist and close up (occlusion) over time. Occlusion of the outflow graft can...
Jagmeet Singh is the founding director of the Resynchronisation and Advanced Cardiac Therapeutics Program. Singh is the principal investigator for the Personalised CRT-MPP Post-Approval Study and a paid consultant for Medtronic. In this commentary he discusses his research on...
The American Heart Journal has published the results of a head-to-head comparison of two patch-based arrhythmia monitoring systems. The study, "Comparison of two ambulatory patch ECG monitors: The benefit of the P-wave and signal clarity" concluded that the BardyDx...
Investigators from the Mayo Clinic and AliveCor demonstrated that a trained artificial intelligence network can help identify people with increased risks of arrhythmias and sudden cardiac death, despite displaying a normal heart rhythm on their electrocardiogram. Up to half...
The SMART Pass sensing filter (Boston Scientific), when in patients implanted with the EMBLEM Subcutaneous Implantable Defibrillator (S-ICD) System, successfully reduces inappropriate shocks. This is the result of an analysis of the LATITUDE database, presented during a late-breaking clinical...
Cardiac contractility modulation (CCM) in heart failure is safe, the results from the FIX-HF-5C randomised controlled trial demonstrate, with all primary and secondary safety endpoints met. The results were presented by William Abraham (Internal Medicine, Division of Cardiovascular Medicine,...
An investigational algorithm, utilising the accelerometer signal in the Micra Transcatheter Pacing System (TPS) (Medtronic) may restore AV synchrony, improving cardiac function in patients with sinus rhythm and atrioventricular (AV) block, the results of a new clinical study show. The...
The first patient has been enrolled and treated in the QDOT AF study (Biosense Webster). The study will evaluate the delivery of high power, short duration ablation with QDOT MICRO, a novel radiofrequency (RF) ablation catheter for the...
Abbott has announced US Food and Drug Administration (FDA) clearance of the Advisor HD Grid mapping catheter, sensor enabled. Advisor HD Grid employs a new design that allows physicians to see things differently, capturing and analysing data in a novel...
This article has been sponsored by Boston Scientific. Case description A 62-year-old woman, with recent sinus venosus atrial septal defect correction surgery, developed a persistent macroreentrant atrial tachycardia and macroreentrant atrial tachycardia (MAT) ablation was performed. The diagnosis of this congenital...
 Acutus Medical has announced that the AcQMap High Resolution Imaging and Mapping System has been utilised for the first time in US patients. The company also revealed initiation of a new clinical study to evaluate the technology during atrial...
Preventice Solutions has announced the launch of the BodyGuardian Mini, the smallest, reusable long-term Holter technology available for cardiac monitoring. The new, compactly designed technology includes an ultra-small, lightweight cardiac monitor that enables up to 14-days of ECG measurements...
The US Food and Drug Administration (FDA) has granted approval for the HeartLight Excalibur Balloon, a next-generation technology designed for the treatment of paroxysmal atrial fibrillation (PAF). The Excalibur Balloon leverages the proven universal balloon design of the company's FDA-approved HeartLight Endoscopic Ablation System and...
The CARTO VIZIGO Bi-directional Guiding Sheath is now available in the United States. This is the first commercially available steerable guiding sheath that can be visualised on the CARTO 3 System during a catheter ablation procedure, helping electrophysiologists reduce dependency...
Stereotaxis has announced a strategic collaboration to integrate the Stereotaxis Niobe Magnetic Navigation System and the Acutus Medical AcQMap High Resolution Imaging and Mapping System with the goal of improving patient care and the physician experience in electrophysiology. “I was...
At the AF Symposium (11–13 January 2018, Orlando, USA) John Camm, St George’s University of London and Imperial College, London, UK, looked at the current status of screening for atrial fibrillation (AF). This is as an area of controversy...
The HAVOC score was developed following the CRYSTAL-AF study, to see if there was an easier way to identify which patients with atrial fibrillation were most at risk of stroke. Susan Zhao, Santa Clara Valley Medical Center, San Jose,...
More patients than ever before are being given NOACs due to their relative stability and safety, but the risk of gastrointestinal bleeding with NOACs is higher than with warfarin. This has led researchers to look for new ways of...
Results from a multicentre study of catheter ablation guided by DEEP (decrement-evoke potential) mapping show that using DEEP mapping meant that ablation was successful in the majority of patients and they could no longer be induced into clinical ventricular...
Medical devices, including cardiovascular implantable electronic devices could be at risk for hacking. In a paper published in the Journal of the American College of Cardiology, the American College of Cardiology’s Electrophysiology Council examines the potential risk to patients...
Local activation mapping at sites of termination of persistent atrial fibrillations (AF) shows repetitive patterns including rotational or focal activity reports a study in Circulation: Arrhythmia and Electrophysiology. Therapy for persistent atrial fibrillation is limited by uncertainty about sustaining mechanisms....
2017 was a year of big results for catheter ablation, continuing the procedure’s steady rise in atrial fibrillation (AF) management. Mark O’Neill, consultant cardiologist and professor of Cardiac Electrophysiology at St Thomas’ Hospital and King’s College London, UK, spoke...

Nassir Marrouche

Nassir Marrouche is a prominent electrophysiologist, executive director of the Comprehensive Arrhythmia Research and Management (CARMA) Centre at the University of Utah in Salt Lake City, USA, and director of the Western Atrial Fibrillation Symposium (23–24 February 2018, Park...
Highlights: Real-time lesion formation and gap detection during ablation: DURABLE-I follow-up Octreotide enables left atrial appendage closure in AF patients with GI bleeding M Edip Gurol: Brain MRI scans can inform the choice between OACs and LAA closure for non-valvular...
LivaNova has finalised the US$190 million sale of its cardiac rhythm unit to MicroPort Scientific. The final terms of the deal commit LivaNova to paying up to US$20 million in indemnity linked to a probe initiated by antitrust officials around...
The US FDA has approved a firmware update that is now available and is intended as a corrective action (recall), to reduce the risk of patient harm due to premature battery depletion and potential exploitation of cybersecurity vulnerabilities for...
A medical device company has announced the results of a clinical study serially conducted at The Icahn School of Medicine, Mount Sinai Hospital, New York, USA and the West Virginia University (WVU) Heart and Vascular Institute, Morgantown, USA. The...
Murj, a healthcare technology company focused on transforming implantable cardiac device management, has announced the availability of OnSite— the industry’s first cloud-based workflow solution for in-office cardiac device management. OnSite is an extension of Murj’s proven workflow for remote transmission...
There is a disparity between indications for and utilisation of implantable cardioverter defibrillators (ICDs) in Asian patients with heart failure, a recent study finds. The results come from a study authored by Yvonne May Fen Chia et al, recently...
A recent study by Marc P Waase (Columbia University Medical Center, New York, USA) et al published in the Journal of the American Medical Association (JAMA) found that abnormal electrocardiograms (ECGs) are common among professional basketball players in the...
Patient safety is the focus of newly published updates to consensus statements that address the use of antithrombotic drugs by individuals who may require regional anaesthesia or interventions targeting acute or chronic pain. The lengthy statements, published in tandem in...
This video has been sponsored by LivaNova. Sleep apnoea is a major chronic disease that can have cardiovascular consequences. Around 40–50% of people with atrial fibrillation (AF) have obstructive sleep apnoea, rising to around 60% in patients with implantable cardiac...
Boston Scientific have announced the acquisition of Securus Medical Group, a privately-held company that has developed a thermal monitoring system for the continuous measurement of oesophageal temperature. Boston Scientific has been an investor in Securus since 2016, and the...
Cardiac health apps and wearable clinical technology is on the rise, along with remote monitoring and wireless connection functionality in implantable cardiac devices. While the amount of clinical trials and published papers on new technology in this field is...
    Wendy Tzou (University of Colorado School of Medicine, Denver, USA) and colleagues at the International Ventricular Tachycardia Ablation Center Collaborative group (IVTCC) published two papers (in Heart Rhythm and Circulation: Arrhythmia and Electrophysiology) in 2017 on the potential impact...
M Edip Gurol is a stroke neurologist with particular expertise in the care of patients at high risk for ischaemic (blockage type) strokes and haemorrhages. His research focuses on clarifying the mechanisms of brain small vessel diseases that increase...
Two real-world analyses featuring the AdaptivCRT algorithm reinforce that its use is linked to a reduction in atrial fibrillation (AF) episodes, as well as tied to higher patient activity levels. The results, involving 408 patients with heart failure and...
One-year results from the CRYO4PERSISTENT AF study of ablation with the Arctic Front Advance Cryoballoon to isolate the pulmonary veins in patients with symptomatic persistent atrial fibrillation (AF). The Arctic Front Advance Cyroablation System is not approved for treating...
The heart is capable of terminating arrhythmias itself after local gene therapy, potentially avoiding the need for patients to undergo painful electric shocks, according to a proof-of-concept study presented at EHRA 2018, a European Society of Cardiology congress. Atrial fibrillation...
Patients with atrial fibrillation could reduce the risk of dementia by taking stroke prevention medications, according to recommendations published online in EP Europace1, a European Society of Cardiology journal, and presented at EHRA 2018.2 The international consensus document was...
Data from the TRUE-HD study has been announced during a late-breaking clinical trial session at the annual congress of the European Heart Rhythm Association (EHRA) in Barcelona, Spain. The data demonstrated the RHYTHMIA Mapping System, when paired with the...
Obese patients are at a higher risk of failed first subcutaneous implantable cardioverter-defibrillator (S-ICD) shocks during defibrillation testing. This is what a group from the University of Pennsylvania, CorVita Science Foundation and Boston Scientific Corporation, all USA, found. The...
Low level of daily physical activity was associated with a higher risk of atrial arrhythmias in heart failure patients with implantable devices. A low level of baseline physical activity was also associated with a higher risk of death of...
The first patient has been enrolled and treated in the SHINE clinical study in Europe. The multicentre study aims to evaluate balloon ablation catheter for safety and effectiveness in achieving pulmonary vein isolation in treatment of paroxysmal atrial fibrillation. The...
Interim data from 228 patients (of which 132 were adjudicated for efficacy) showed that AndexXa rapidly and significantly reversed anti-Factor Xa activity (the anticoagulant mechanism of these drugs) when administered as a bolus, and sustained this reversal when followed...
New late-breaking clinical trial data from the MOMENTUM 3 clinical study shows overall survival of 83% at 2-years and marked improvement in clinical outcomes for our patients suffering with advanced heart failure. The data were published online in The New...
EBR Systems has announced enrollment of the first patients in the global SOLVE-CRT (Stimulation of the Left Ventricular Endocardium for Cardiac Resynchronisation Therapy) clinical trial. The first patients were enrolled by Christian Butter at Immanuel Klinikum Herzzentrum Brandenburg in...
iRhythm Technologies has announced primary results of the mHealth Screening to Prevent Strokes (mSToPS) study that evaluated detection of silent atrial fibrillation (AF) in high-risk individuals using Zio by iRhythm. Electrocardiogram (ECG) recording and analysis were carried out using the...
Fysicon has announced that it has been acquired by Canon Medical Systems Corporation (Otawara, Japan).   Linda Elberse, chief executive officer of Fysicon said, "Being part of a major player as Canon Medical Systems Corporation gives us the opportunity to...
AblaCor medical corporation has announced that it has received a notice of allowance from the United States Patent & Trademark Office on five additional patents for its CircumBlator AFib catheter ablation system to advance pulmonary vein isolation ablation procedures for patients with atrial...
Survival from cardiac arrest doubled when a bystander stepped in to apply an automated external defibrillator (AED) before emergency responders arrived, according to new research published in the journal Circulation. Researcher looked at 49,555 cardiac arrests across the USA and...
CardioFocus have announced the initiation of a clinical evaluation of the new HeartLight X3 system for the treatment of AF. Building upon the advanced features of the current HeartLight endoscopic ablation system—direct tissue visualisation, titratable laser energy, and compliant balloon technology—HeartLight X3 is...
Medtronic is recalling certain implantable cardioverter defibrillators (ICDs) and cardiac resynchronisation therapy defibrillators (CRT-Ds) due to a defect in the manufacturing process.  This defect causes an out of specification gas mixture inside the device and may prevent the device...
EPD’s Cardiac Mapping and Navigation System  has received CE mark approval.  The system helps electrophysiologists navigate the heart by generating an accurate 3D map, while imaging and pinpointing the exact location and orientation of catheters in the heart during...
AtriCure, Inc., a leading innovator in treatments for atrial fibrillation and left atrial appendage management, has announced that it has launched the AtriClip FLEX•V Left Atrial Appendage (LAA) Exclusion System in the United States. The new AtriClip FLEX•V is...
The FDA is advising caution before prescribing the antibiotic clarithromycin (Biaxin) to patients with heart disease because of a potential increased risk of heart problems or death that can occur years later. The FDAs recommendation is based on a...
Felix Weise (Cardioangiologisches Centrum Bethanien, Frankfurt, Germany) and others report in EuroIntervention that a strategy of six weeks’ duration of dual antiplatelet therapy (DAPT) followed by lifelong aspirin “appears to be a viable alternative” to existing antithrombotic regimens in...
New data from the EXCEL trial, which found that percutaneous coronary intervention (PCI) was non-inferior to coronary artery bypass grafting (CABG) at three years in patients with left main disease, indicate that CABG patients have a significantly increased risk...
Cardiva Medical, an innovator in the field of vascular closure, has announced that the company has closed on US$11 million in additional financing – bringing total equity and debt financing in the current round to US$41 million. The additional financing...
The Food and Drug Administration (FDA) has today issued the final rule on “human subject protection; acceptance of data from clinical investigations for medical devices”. The rule updates the FDA’s standards for accepting clinical data from clinical investigations conducted...
A miniature leadless pacemaker was safe and effective at three years in the first-in-human LEADLESS study, according to a research letter published in Circulation. However, one patient experienced a complication related to battery malfunction, which led to a battery advisory...
African Americans with atrial fibrillation (AF) have a significantly higher risk of stroke than Caucasians with the condition, according to new research published in HeartRhythm by researchers from the Perelman School of Medicine at the University of Pennsylvania, USA. The new findings...
A collaborative study, has found that older patients with atrial fibrillation (AF) undergoing cardiac surgery accompanied with surgical left atrial appendage closure had a lower risk of readmission for thromboembolism over the following 3 years. The study was carried...
Biosense Webster, a Division of Johnson & Johnson Medical NV/SA, and a leader in the diagnosis and treatment of cardiac arrhythmias, recently presented new data evaluating the one-year outcomes of atrial fibrillation (AF) ablation using the CARTO 3 System CARTO...
Written by Hannah Woolley, Cardiac Rhythm News Editor Heart imaging has been successfully used to predict the benefit or futility of catheter ablation. The investigators described their findings in the Journal of the American College of Cardiology: Cardiovascular Imaging. Around 20–30% of...
Philips is recalling the HeartStart MRx defibrillator due to a defect in the device's gas discharge tube. The gas discharge tube has micro cracks which allows internal gasses to escape and causes the tubes to not function as expected....
A recent study by Gry Haaland (University of Bergen, Bergen, Norway) et al published in the Journal of the American Association of Medicine (JAMA): Internal Medicine points to a possible association between warfarin use among patients older than 50...
Acesion Pharma, a Danish biotech company developing novel treatments for atrial fibrillation (AF), the most common cardiac arrhythmia, announced it has received approval to commence its first clinical study for its lead compound AP30663. The phase 1 study in...
Highlights: Less bleeding in ablation with interrupted dabigatran compared to uninterrupted warfarin Successful ablation for ventricular tachycardia associated with markedly reduced mortality in advanced heart failure patients Natalia Trayanova: Imaging-based simulations for predicting sudden death and guiding ablation Nassir Marrouche: Profile https://o6xux43a6gs4eidym2svvhon-wpengine.netdna-ssl.com/wp-content/uploads/sites/12/2018/02/Cardiac-Rhythm-News-issue-39-low-res.pdf
  Respicardia, Inc., a medical technology company developing therapies that improve cardiovascular health, have announced the first U.S. commercial case using the remedē system to treat central sleep apnoea was completed at The Ohio State University Wexner Medical Center in...
Natalia Trayanova envisions the future of cardiology and electrophysiology advancing through personalised medicine and computational simulations. Trayanova is the director of the Computational Cardiology Lab at Johns Hopkins University (Baltimore, USA), as well as the Murray B Sachs professor...
Local activation mapping at sites of termination of persistent atrial fibrillations (AF) shows repetitive patterns including rotational or focal activity reports a study in Circulation: Arrhythmia and Electrophysiology1. Therapy for persistent atrial fibrillation is limited by uncertainty about sustaining mechanisms. ...
The results of the CASTLE-AF study, published today in the New England Journal of Medicine, show that patients treated with radiofrequency catheter ablation rather than traditional drug therapies for atrial fibrillation had improved outcomes. “This clinical trial is the first time...
Following EHRA’s decision to hold its own annual congress in March and the difficulty for the industry to financially support Cardiostim as well as before, the decision has been taken no to hold Cardiostim 2018. In spite of the extraordinary...
  Boston Scientific Corporation today announced it has closed an investment and entered into an acquisition option agreement with Millipede, Inc., a privately-held company that has developed the  ring system for the treatment of severe mitral regurgitation (MR). Under the terms of the...
The results of ABRIDGE-J, a Japanese multicentre randomised study on minimally interrupted dabigatran vs. uninterrupted warfarin for catheter ablation, were presented during a late-breaking trials session at the American Heart Association (AHA) Scientific Sessions (11–15 November 2017, Anaheim, USA)....
Imricor Medical Systems announced today the completion of enrolment for the clinical study to evaluate Imricor’s Vision-MR Ablation Catheter for the treatment of atrial flutter under real-time magnetic resonance imaging (MRI) guidance. The single-centre study enrolled 35 patients and was...
In October 2017, the American Heart Association/American College of Cardiology/Heart Rhythm Society (AHA/ACC/HRS) released a guideline document on the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death (SCD): a guideline document for healthcare professionals....
Vital USA Inc., a healthcare internet-of-things (IoT) vital sign company announced at the Consumer Technology Association's annual meeting (CES; 9-12 January, Las Vegas, USA) the release of the Vital Moto Mod: mobile monitoring platform featuring the first fully integrated platform to measure...
The US Food and Drug Administration (FDA) is providing information and recommendations regarding the Zoll LifeVest 4000 due to concerns that the device may fail to deliver treatment to the patient if the device is not replaced soon after...
The Janssen Pharmaceutical Companies of Johnson & Johnson has announced findings from the US Food and Drug Administration's (FDA) mini-sentinel assessment, confirming the positive safety and efficacy profile of Xarelto (rivaroxaban) established in the phase III ROCKET AF clinical trials,...
  Nearly a quarter of patients with chronic ischaemic cardiovascular disease are dead or hospitalised within six months, reports a European Society of Cardiology (ESC) study published in the European Journal of Preventive Cardiology.1 The Chronic Ischaemic Cardiovascular Disease (CICD) pilot registry...
  The cardiovascular magnetic resonance (CMR) 2018 meeting organised by European Association of Cardiovascular Imaging and the Society for Cardiovascular Magnetic Resonance will showcase the latest advances in CMR, and how they are improving patient care and outcomes. CMR 2018 will...
iMedrix, a Silicon Valley and Bangalore-based mHealth start up company, has announced the general availability of its product KardioScreen, a CE certified mobile and portable hospital-grade digital electrocardiogram (ECG). The system uses connected technology, bringing a “deep internet-of-things (IoT) architecture...
A study on substernal pacing acute clinical evaluation (SPACE) by Darius Sholevar (Our Lady of Lourdes Medical Center, Camden, USA) et al published in the Heart Rhythm journal has investigated the feasibility of extravascular pacing using a novel substernal electrode...
Abbott has announced the US Food and Drug Administration (FDA) approval for magnetic resonance (MR)-conditional labelling for the Quadra Assura MP cardiac resynchronisation therapy defibrillator (CRT-D) and Fortify Assura implantable cardioverter defibrillator (ICD), two of the company's most widely-used...
NightBalance, a Netherlands-based company developing obstructive sleep apnoea (OSA) therapies, has announced that the Dutch National Health Care Institute (ZIN) issued a positive recommendation to include its sleep apnoea therapy for reimbursement. The recommendation was issued to the Sleep...
This video has been sponsored by Abbott. The Confirm Rx implantable cardiac monitor (ICM) is the world’s first and only insertable cardiac monitor that combines a quick and minimally invasive procedure with Bluetooth wireless technology, allowing patients to connect using...
A recent study by Lu-Chen Weng (Massachusetts General Hospital, Boston, USA) et al which aimed to quantify and systematically characterise the genetic architecture of atrial fibrillation (AF) has found that genetic variation contributes substantially to AF susceptibility and risk. The...
The Optimizer system developed by Impulse Dynamics has received approval from the China Food and Drug Administration (CFDA). The Optimizer is an implantable cardiac contractility modulation therapy device for chronic heart failure patients. It is the only device therapy...
A retrospective national Swedish registry study by Leif Friberg and Mårten Rosenqvist (Karolinska Institutet, Stockholm, Sweden) has found that the risk of dementia is higher in atrial fibrillation (AF) patients without oral anticoagulant (OAC) treatment. The paper was presented...
The Heart Rhythm Society (HRS), in partnership with WebMD Education, has announced the launch of a free online educational tool for atrial fibrillation (AF). The new interactive AF information tool is part of a larger series of educational activities hosted by WebMD Education to help patients,...
A cluster analysis of the data from the ORBIT-AF observational registry study has been published by Taku Inohara (Duke University Medical Center, Durham, USA) et al in the Journal of the American Medical Association (JAMA). The cluster analysis of...
A small study by Phillip S Cuculich (Washington University School of Medicine, St Louis, USA) et al has shown that  radiation therapy, commonly used to treat cancer, can be used as a noninvasive radioablation approach to treat patients with...
Janssen has submitted a supplemental new drug application to the US FDA for two new indications for rivaroxaban (Xarelto, which is marketed by Bayer in Europe): reducing the risk of major cardiovascular events such as cardiac death, myocardial infarction or...
AliveCor has announced the issuance of a US patent which covers the use of data collected from wearable devices as a means of assisting diagnoses of cardiac arrhythmias, including those that may be asymptomatic. US Patent Number 9,839,363, entitled "Discordance...
Apple has launched the Apple Heart Study app, a first-of-its-kind research study using Apple Watch’s heart rate sensor to collect data on irregular heart rhythms and notify users who may be experiencing atrial fibrillation (AF). To calculate heart rate and rhythm, the...
Imricor is developing a magnetic resonance (MR) compatible injection catheter and has announced a joint development agreement with MiRTLE Medical to integrate MiRTLE’s MR compatible 12-lead ECG system with Imricor’s Advantage-MR EP Recorder/Stimulator System. This integration, along with Imricor’s MR...
Following a priority review by US Food and Drug Administration (FDA), evolocumab has received FDA approval in the USA. The drug is a PCSK9 inhibitor for reducing risk of myocardial infarction (MI), stroke and coronary revascularisation.   Pharmaceutical company Amgen has...
AliveCor has added another personal electrocardiogram (ECG) technology product to their range, announcing the US Food and Drug Administration (FDA) have cleared the Kardia Band in the USA. The Kardia Band works exclusively with the Apple Watch, providing owners of...
The Journal of the American Medical Association (JAMA) have published new guidelines on diagnostic testing for obstructive sleep apnoea (OSA) in adults. The new guidelines, authored by Babak Mokhlesi and Adam S. Cifu at the University of Chicago, USA, include updated...
NeuroproteXeon has announced the publication of a second finding from a randomised, controlled phase II trial of inhaled xenon and oxygen combined with hypothermia for out-of-hospital cardiac arrest patients. The study, which appeared in the Journal of the American...
EBR Systems has raised US$50 million to conduct the global SOLVE-CRT (stimulation of the left ventricle endocardially) study. SOLVE-CRT is a pivotal clinical trial intended to establish safety and efficacy in support of US Food and Drug Administration (FDA) approval WiSE (wireless stimulation endocardially), a product...
Acute myocardial infarction (MI) and stroke patients without medical insurance in the USA face “devastating” and catastrophic health expenses that can bankrupt them, new research shows. The study by Rohan Khera (University of Texas Southwestern Medical Centre, Dallas, USA)...
LivaNova has entered a binding letter of intent for the sale of its cardiac rhythm management business franchise to Shanghai-based company MicroPort for $190 million in cash. The companies, which have previously worked together in a joint venture, recently...
1. The "ILL-CONCEIVED" pallas study may be relaunched John Camm "I want to say just a few quick words about dronedarone", John Camm (St George's University of London and Imperial College, London, UK) told the audience of his talk at the Europe...
  A study published in the Circulation journal has shown that the risk of atrial fibrillation (AF) in young adults and children who suffer from congenital heart disease (CHD) was 22 times higher than in a matched control group. The study...
A new comparative study between dabigatran and warfarin finds similar ischemic stroke risks, but fewer brain bleeds for dabigatron compared with warfarin in US-based national drug surveillance network. More research is needed however, to determine whether dabigatran is associated...
Boehringer Ingelheim has announced results from two new analyses of the phase III RE-VERSE AD study, which evaluated the safety and efficacy of idarucizumab, marketed in the USA as Praxbind, in reversing the anticoagulant effect of Pradaxa (dabigatran etexilate...
Rivaroxaban vascular dose, 2.5 mg twice daily, plus aspirin 100 mg once daily also significantly (p=0.0003) reduces the risk of the composite outcome of major cardiovascular events, major adverse limb events and major amputation in patients with peripheral artery...
Presenters at the American Heart Association (AHA)’s annual Scientific Sessions (11-15 November 2017; Anaheim, USA) have identified the lack of awareness of automated external defibrillators (AEDs) in Latinos, as well as a general reluctance in bystanders to perform CPR...
Aziyo Biologics has announced the launch of their CanGaroo bio envelope specifically for use with subcutaneous implantable cardioverter-defibrillators (S-ICDs). It is the only cardiac implantable electronic device (CIED) envelope available for use with S-ICDs. CanGaroo is a natural extracellular matrix (ECM)...
Boston Scientific has announced the final five-year outcomes data from the PREVAIL study during a late-breaking clinical trial session at this year’s Transcatheter Cardiovascular Therapeutics (TCT; 29 October-2 November 2017, Denver, USA. The data, in combination with five-year outcomes...
Recycling or reusing cardiac implantable electronic devices (CIEDs) could bring down costs for low-income or uninsured patients. A small study presented at the 30th Mexican Congress of Cardiology (2-5 November, 2017; Guadalajara, Mexico) has shown that doctors were able...
In Illinois, USA, Jesus Garcia has become the first patient in his state to receive the HeartMate 3 (Abbott/St. Jude Medical) left ventricular assist device (LVAD), a new option for physicians managing advanced heart failure patients in need of...
The American College of Cardiology (ACC), along with the American Heart Association (AHA) and the Heart Rhythm Society (HRS) has published new guidelines for the treatment of patients with ventricular arrhythmias and the prevention of sudden cardiac death. The...
Analytics 4 Life, a digital health company applying artificial intelligence to improve and develop existing care pathways, has announced it will be presenting new clinical data on the company's ongoing Coronary Artery Disease Learning and Algorithm Development (CADLAD) study...
Published in the Journal of the American College of Cardiology (JACC): Clinical Electrophysiology, Björkenheim et al’s study of patient- and physician-reported outcomes of atrial fibrillation (AF) ablation has analysed the complex variables and subjectivity in assessing AF-related symptoms. The...
Nexeon MedSystems has announced its completion of an initial series of clinical studies evaluating the utilization of transcutaneous auricular vagus nerve stimulation (aVNS) for the relief of paroxysmal atrial fibrillation.  The company was previously awarded a €3.4M research grant...
Acutus Medical has announced that the US Food and Drug Administration (FDA) cleared the AcQMap high resolution imaging and mapping system as well as the AcQMap 3D imaging and mapping catheter for use in patients for whom electrophysiology procedures...
A Korean nationwide cohort study by Tae-Hoon Kim et al has shown that truly low-risk Asian patients with atrial fibrillation (AF) for stroke can be identified using the CHA2DS2-VASc score. The study was published in the American Heart Association/American Stroke...
This video has been sponsored by LivaNova. AF is a growing epidemic affecting 33.5 million people today.1 Up to 91% of AF patients have co-morbidities.2 Among these co-morbidities, the guidelines highlight the need to pay attention to sleep apnea.3 Like asymptomatic...
Boston Scientific has announced key data will be presented at next week’s Transcatheter Cardiovascular Therapeutics (TCT) meeting (29 October–2 November, Denver, USA). For example, on 2 November, data for the Watchman left atrial appendage closure device will be featured...
The US Food and Drug Administration (FDA) has approved Abbott St. Jude Medical’s Confirm Rx insertable cardiac monitor (ICM), a smartphone compatible ICM designed to help physicians remotely identify cardiac arrhythmias. The device may provide a new way for patients...
The risk of atrial fibrillation (AF) is increased in subclinical hyperthyroidism, but it has been is uncertain whether variations in thyroid function within the normal range or subclinical hypothyroidism are also associated with AF. A study published in Circulation...
  In October 2016, St. Jude Medical recalled a subset of implantable cardioverter defibrillators (ICDs) and cardiac resynchronisation therapy defibrillators (CRT-Ds) due to reports of rapid battery failure. To address the issue, the company has released a battery performance alert...
Respicardia has received US Food and Drug Administration (FDA) approval of its remedē system, a transvenous implantable neurostimulation device that stimulates the phrenic nerve and engages the diaphragm to restore natural breathing during sleep in patients with central sleep apnoea...
The American College of Cardiology (ACC), Heart Failure Society of America (HFSA), Heart Rhythm Society (HRS) and Society for Cardiovascular Angiography and Interventions (SCAI) have announced a partnership to develop new modules to help subspecialty cardiologists—interventional cardiologists, electrophysiologists, and...
Abott has announced Conformité Européenne (CE) Mark for 3 Tesla (T) magnetic resonance-conditional labelling for both the Assurity MRI pacemaker and the Tendril STS pacing lead. Patients implanted with these low-voltage devices will have the ability to undergo full-body...
A study published in the American Heart Association’s journal Circulation has found that men develop atrial fibrillation (AF) about a decade earlier than women on average, and being overweight is a major risk factor. Untreated AF increases the risk of heart-related...
  A retrospective study conducting a safety assessment and comparison between two percutaneous devices commonly used for left atrial appendage (LAA) closure in the US­ has shown a significant increase in reported safety events following US FDA approval of the...
According to the results of the EMANATE trial, patients with atrial fibrillation (AF) who receive apixaban (Eliquis, Bristol-Myers Squibb/Pfizer) before undergoing elective cardioversion of patients with atrial fibrillation to normal sinus rhythm have a lower risk of stroke than...
Pamela B Morris has been selected as the next vice chair of the American College of Cardiology (ACC) annual scientific session. She will serve as vice chair for ACC.19 and ACC.20, and will transition to chair for ACC. 21...
Catheter ablation of atrial fibrillation significantly reduces mortality and hospitalisation in atrial fibrillation patients with heart failure in comparison with conventional treatment, data from the CASTLE-AF trial suggest. Investigators Nassir Marrouche (University of Utah Health Care, Salt Lake City,...
Two novel smartphone and tablet applications (apps) for atrial fibrillation patients and healthcare professionals have been launched by heart experts. The two apps will communicate to maximise face-to-face time. The objectives and design of the apps are outlined in...
Closure of the left atrial appendage during open heart surgery protects the brain from infarctions and stroke, and could be routinely performed in the future, according to the findings from a late-breaking trial presented at the European Society of Cardiology...
Highlights: - Catheter ablation lowers mortality in atrial fibrillation patients with heart failure - Thrombus formation on LAA occlusion devices strongly associated with higher risk of ischaemic stroke - Profile: Sabine Ernst - EHRA: Inventors Award https://o6xux43a6gs4eidym2svvhon-wpengine.netdna-ssl.com/wp-content/uploads/sites/12/2017/10/38-Cardiac-Rhythm-News-EU.pdf  

Sabine Ernst

Sabine Ernst (lead electrophysiology research/consultant cardiologist, Royal Brompton and Harefield Hospital, London, UK and associate lead for Cardiac Imaging in the Biomedical Research Unit of the Royal Brompton Hospital) set up the first magnetic navigation catheter ablation laboratory in...
Highlights: - Catheter ablation lowers mortality in atrial fibrillation patients with heart failure - Thrombus formation on LAA occlusion devices strongly associated with higher risk of ischaemic stroke - Profile: Sabine Ernst - EHRA: Inventors Award https://o6xux43a6gs4eidym2svvhon-wpengine.netdna-ssl.com/wp-content/uploads/sites/12/2017/10/38-Cardiac-Rhythm-News-US.pdf
Peerbridge Health has announced that its first product, the Peerbridge Cor System—a wireless electrocardiogram (ECG) monitor—has received 510(k) clearance from the US Food and Drug Administration (FDA). The patented device has the smallest on-body footprint of any wearable monitor...
Boston Scientific Corporation has announced a definitive agreement to acquire Apama Medical, a privately-held company that is developing the Apama Radiofrequency (RF) Balloon Catheter System for the treatment of atrial fibrillation (AF). The transaction consists of US$175 million in cash up-front and a...
The US Food and Drug Administration (FDA) has approved Medtronic’s HeartWare HVAD system as a destination therapy for patients with advanced heart failure who are not candidates for heart transplants. Designed to help the heart pump, the left ventricular assist...
A study has shown modified human factor X to be a safe and effective reversal agent for prevention and treatment of bleeding in patients taking factor Xa oral anticoagulants. This new therapeutic factor X was inspired by a snake...
LivaNova and MicroPort’s Shanghai-based joint venture—MicroPort Sorin Cardiac Rhythm Management—has obtained approval for Rega. The family of pacemakers is now approved by the China Food and Drug Administration. Rega are the first pacemakers manufactured by the venture, as well as...
CardioFocus’ HeartLight Excalibur Balloon has been granted CE mark. The technology is designed for the treatment of atrial fibrillation. The Excalibur balloon builds on the universal balloon design of the company’s HeartLight endoscopic ablation system. It is intended to optimise...
The American College of Cardiology (ACC) and the American Heart Association (AHA) have released updated clinical performance and quality measures to benchmark and improve the quality of care for adult patients hospitalised with ST-elevation and non–ST-elevation myocardial infarction (STEMI...
The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has issued a positive opinion for an update to the European Summary of Product Characteristics (SmPC) of dabigatran etexilate (Pradaxa, Boehringer Ingelheim) for the...
  Boston Scientific has launched the Resonate family of implantable cardioverter defibrillator (ICD) and cardiac resynchronisation therapy defibrillator (CRT-D) systems featuring the HeartLogic Heart Failure Diagnostic to help physicians improve heart failure (HF) management. The new devices, which are approved...
A study led the University of Warwick, Coventry, UK, has suggested that people are reluctant to use public access defibrillators (AEDs) to treat cardiac arrests. The analysis of existing international studies, which has been published in the European Heart Journal,...
Abbott has received US Food and Drug Administration (FDA) approval for magnetic resonance (MR)-conditional labelling for one of the company’s most widely-used implantable cardioverter defibrillators (ICD) and associated high voltage leads. The approval of MR-conditional labelling for the Ellipse...
The president of the American College of Cardiology (ACC), Mary Norine Walsh, has said that “it is concerning” that the Graham-Cassidy proposal (for US healthcare reform) is “being rushed to the Senate floor not only at the expense of...
The results of CLOSE, Gore Reduce and the extended follow-up of RESPECT—all published in The New England Journal of Medicine—indicate that percutaneous closure of patent foramen ovale (PFO) is associated with a significant reduction in ischaemic stroke in patients...
Pauline Quenin (I’institut du thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, Nantes, France) and others report in Circulation Arrhythmia and Electrophysiology that a quarter of families who underwent screening after the sudden unexplained death of a young relative were...
A new study has found that beta blockers are not needed after a heart attack if survivors are taking ACE inhibitors and statins. The study is the first to challenge the current clinical guideline that heart-attack survivors should take...
According to a new survey, the average age and income of cardiologists in the US are increasing. The fifth annual Cardiovascular Provider Compensation & Production Survey from MedAxiom has revealed that one in five cardiologists are over 61 years...
Experts at Queen’s University Belfast, Belfast, UK, have designed a flexible battery that could provide an alternative to the rigid batteries that usually power medical implants. Currently, devices such as pacemakers, defibrillators and neurostimulators are fitted with rigid and metal...
Boston Scientific has announced new data from the MultiSENSE (Multisensor chronic evaluation in ambulatory heart failure patients) study, which is evaluating the performance of the HeartLogic heart failure diagnostic to predict impending heart failure decompensation. Results from the study...
The committee for medicinal products for human use (CHMP) of the European Medicines Agency (EMA) has issued a positive opinion for an update to the European summary of product characteristics of dabigatran (Boehringer Ingelheim) for the treatment of patients...
The Heart Rhythm Society (HRS) has issued an international consensus statement that comprehensively addresses lead management for patients with cardiovascular implantable electronic devices (CIEDs). The expert consensus statement, which was presented at the 10th Asia Pacific Heart Rhythm Society (APHRS)...
Fysicon has announced that it has received 510(k) FDA clearance for its QMAPP haemodynamic monitoring system. A press release reports that QMAPP offers cardiologists the most advanced technology available in haemodynamic monitoring. It adds that QMAPP amplifier has the...
PaceMate has announced the appointment of Kevin Campbell as its new chief executive officer (CEO). A press release reports that Campbell’s work as a leading cardiologist—combined with his past roles as CEO at K-Roc Healthcare Consulting and advisor to...
The latest results from one of the largest, ongoing global disease registries in atrial fibrillation (AF)— GARFIELD-AF (global anticoagulant registry in the field-atrial fibrillation) —show that there are significant differences in the characteristics of patients with AF in Asia...
AtriCure has launched its AtriClip Pro•V left atrial appendage exclusion system in the USA. A press release reports that the new device offers an open-ended design combined with a tip-first closure mechanism to enable easier navigation and placement when...
There is a lack of sufficient data about the effect of racial differences on outcomes following an out-of-hospital cardiac arrest. Therefore, Karuppiah Arunachalam and colleagues—using results from the national inpatient sample (NIS) database—sought to determine what role (if any)...
AliveCor, the leader in FDA-cleared personal ECG technology, have announced the results of four clinical research presentations that demonstrate that AliveCor's hyper-fast, 30 second, digital ECG can positively impact and potentially even save the lives of millions of people...
New subanalysis data demonstrate edoxaban (Lixana, Daiichi Sankyo) provide comparable efficacy and greater safety compared to warfarin, across non-valvular atrial fibrillation patients with different stroke risk scores. The findings are based on a subanalysis of the ENGAGE AF-TIMI 48...
The first health economics data from GARFIELD-AF (Global anticoagulant registry in the field–atrial fibrillation) was presented at the European Society of Cardiology (ESC) congress (26–30 August, Barcelona, Spain). These data demonstrate that atrial fibrillation imposes a high financial, economic...
The COMPASS study, which was presented at the European Society of Cardiology (ESC) congress (26–30 August, Barcelona, Spain), has shown that rivaroxaban (Xarelto, Bayer) 2.5mg twice daily, plus aspirin 100mg once daily, is associated with a 24% relative risk...
At the European Society of Cardiology (ESC) congress (26–30 August, Barcelona, Spain), the European Heart Rhythm Association (EHRA) released an analytical supplement to the 10th EHRA White Book. The EHRA White Book, which is supported by Biotronik, is the annual...
Data from the EMANATE trial, which was presented at a Hot Line session of the European Society of Cardiology (ESC) congress (26–30 August, Barcelona, Spain), indicate that the risk of stroke is significantly lower in atrial fibrillation patients who...
The FDA has approved the Full MagLev HeartMate 3 (Abbott) left ventricular assist device for use in heart failure patients in need of short-term haemodynamic support (eg. bridge-to-transplant or bridge to myocardial recovery). The device, a press release reports,...
Abbott has initiated a US pivotal clinical study evaluating the safety and effectiveness of a modified version of its Amplatzer device to correct patent ductus arteriosus—a common congenital heart defect that occurs in approximately 80,000 preterm infants in the...
The RE-DUAL PCI trial indicates that dual therapy with the non-vitamin K antagonist oral anticoagulant dabigatran (Pradaxa, Boehringer Ingelheim)—and not aspirin—and a P2Y12 inhibitor is associated with a significant reduction in major bleeding, compared with conventional triple therapy, in...
Preliminary results from the ABLATOR observational registry have shown similar success rates (around 58%) in first time ablation and repeat ablation for persistent atrial fibrillation (AF) ablation procedures with contact force sensing technology after one year of follow-up. A...
Jonathan Behar (London, UK) co-inventor for the Guide CRT platform—shortlisted as a 2017 finalist for the EHRA Inventors Award—details the benefits of this novel technology, which enables the real-time analysis and fusion of cardiac magnetic resonance imaging (MRI)-derived scar...
For the second-year running, the European Heart Rhythm Association (EHRA) held the EHRA Inventors Award competition at EHRA-EUROPACE CARDIOSTIM (18‒21 June, Vienna, Austria), a key activity part of the EHRA Innovation Forum which seeks to facilitate innovation in the...
Behzad Pavri (Thomas Jefferson University Hospital, Philadelphia, USA) is an advocate for re-use of cardiac implantable electronic devices (CIEDs) as life-saving medical technology for patients in low-income countries, which in most cases have limited access to them. For the...
Inspired by the 2017 Heart Rhythm Society (HRS) Scientific Sessions opening plenary theme “Becoming a citizen of the world” and the key speaker, Hugh Evans (humanitarian, social entrepreneur and co-founder/chief executive officer at Global Citizen/Global Poverty Project), HRS highlighted...
Medtronic has received CE mark for the Attain Stability Quad MRI SureScan left heart lead. The device offers active-fixation technology, designed for precise lead placement and stability. The company has undertaken a limited European launch, with the first commercial implants...
The US Food and Drug Administration has approved Biotronik’s Edora HF-T QP magnetic resonance (MR)-conditional cardiac resynchronisation therapy pacemaker (CRT-P). The device—which features MRI AutoDetect technology—has now been commercially launched by the company in the USA. Outside of the USA,...
New research has discovered a potential means to trigger damaged heart cells to self-heal. For the first time, researchers have identified a long non-coding ribonucleic acid (ncRNA) that regulates genes controlling the ability of heart cells to undergo repair...
ARCA biopharma has announced the completion of enrolment for GENETIC-AF. This Phase 2B, double-blind, superiority clinical trial is evaluating bucindolol hydrochloride (Gencaro) as a potential genetically-targeted treatment for atrial fibrillation (AF). ARCA expects to report top-line Phase 2B data...
Physicians identified a majority of patients with advanced heart failure as at high risk for transplant, left ventricular assist device (LVAD) or death while few of those patients considered themselves to be at high risk, according to a study...
Marijuana use is associated with a three-fold risk of death from hypertension, according to research published in the European Journal of Preventive Cardiology. “Steps are being taken towards legalisation and decriminalisation of marijuana in the USA, and rates of recreational...
Portola Pharmaceuticals has announced that the US Food and Drug Administration (FDA) has found its resubmitted Biologics License Application andexanet alfa (AndexXa) to be acceptable for review, with an action due date of 2 February 2018. The resubmission includes supplemental...
Children from socially and economically disadvantaged families and neighborhoods appear more likely to have thicker carotid artery walls. In adults, this may indicate higher risk for heart attack and stroke in later life. “We know that socioeconomically disadvantaged people are...
The first study to assess the clinical impact of remote monitoring with the Reveal LINQ implantable loop recorder (Medtronic) has demonstrated the benefits of this feature in early diagnosis of asymptomatic but serious arrhythmias in a significant proportion of...
When speaking on therapy of vasovagal syncope (VVS), it is important to stress that a specific treatment of VVS is only rarely necessary in clinical practice. Indeed, in the majority of patients, VVS is a benign condition that does...
By Angela Gonzalez A retrospective study, including the largest series of patients with refractory ventricular tachycardia undergoing cardiac sympathetic denervation for structural heart disease, has shown freedom from ventricular tachycardia/implantable cardioverter defibrillator (ICD) shock, heart transplant death of 50% at...
Stereotaxis and Princess Grace Hospital in Monaco have announced the publication of a study comparing the speed of lesion formation of magnetic catheters using the Niobe system to manually controlled contact force catheters. The analysis, published online in the Journal of Cardiovascular Electrophysiology (DOI: 10.1111/jce.13222), included 1,008...
Pneumonia or sepsis in adults that results in hospital admission is associated with a six-fold increased risk of cardiovascular disease in the first year, according to research published in the European Journal of Preventive Cardiology. Cardiovascular risk was more...
CardioFocus has announced that the Japanese Ministry of Health, Labour and Welfare has approved the HeartLight Endoscopic Ablation System for the treatment of paroxysmal atrial fibrillation (AF) in Japan.  The HeartLight System is a visually-guided laser balloon technology for controlled and consistent...
National charity, Heart Research UK has granted funding for an innovative research project with University College London, UK, and Great Ormond Street Hospital, London, UK, which aims to pioneer a new imaging technique that may benefit babies born with...
By Angela Gonzalez People working 55 hours or more a week had an approximately 40% higher risk of atrial fibrillation compared with people working 35 to 40 hours a week, a large multi-cohort, 10-year study has found. Nine out of ten...
Physicians in internal medicine and geriatrics and even physicians working in cardiology departments lack basic knowledge of treatment with implantable cardioverter defibrillators (ICDs) and how to clinically manage these patients, according to a stratified questionnaire survey conducted in Sweden.  The...
The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has issued a positive opinion on a label update regarding the use of 15mg once-daily of the oral Factor Xa inhibitor rivaroxaban (Xarelto, Bayer)...
The US Food and Drug Administration (FDA) has approved Biotronik’s Intica DX and Intica cardiac resynchronisation therapy (CRT)-DX implantable cardioverter defibrillator (ICD) systems, which are now available for sale. DX technology is designed to eliminate the need for an atrial...
The European Commission has granted marketing authorisation for sodium-free potassium binder, patiromer (Valtessa; Vifor Fresenius Medical Care Renal Pharma, Vifor UK), for the treatment of hyperkalaemia in adults. Robert Lewis, consultant nephrologist and chief of Service of the Wessex Kidney...
Gaining even a little weight over time may alter the structure and function of heart muscle, affecting long-term risk of heart failure, according to new research published in Journal of the American Heart Association. Researchers followed 1,262 adults (average age...
AliveCor has announced a collaboration with Mayo Clinic to develop tools for medical and non-medical personnel to easily screen for long QT syndrome (LQTS) early by combining AliveCor’s artificial intelligence (AI) technology with Mayo’s patented algorithms. Through this collaboration, new...
A review appearing in the Journal of the American College of Cardiology (JACC) has highlighted Vectorious Medical Technologies, an Israeli company developing the world’s first digital wireless sensory implant for measuring left atrial pressure (LAP; currently available CardioMEMS technology...
For the first time this year, late-breaking clinical trials session were held at the Asian Pacific Society of Cardiology (APSC) Congress, to highlight world-class research coming out of the region. The ASIAN-HF registry, which was presented at the late-breaking clinical...
The Heart Rhythm Society (HRS) has announced eight US facilities to be awarded funding to support the development of the 2017 AFib Screening and Education initiative. The programme is designed to increase awareness of atrial fibrillation among patients and caregivers, support...
A French multicentre analysis of left atrial appendage (LAA) occlusion for stroke prevention in atrial fibrillation patients has found a 5.3% rate of thrombus formation on left atrial appendage occlusion devices. Authors of the study consider “this is not...
Cardiac Insight, a US developer of wearable medical devices and diagnostic software, has announced that its US Food and Drug Administration (FDA)-approved Cardea Solo electrocardiogram monitoring system is now available for diagnosing atrial fibrillation following cardiac ablation. According to a...
National Institutes of Health (NIH) funding to conduct cardiac arrest research has dwindled in the last decade, and is a fraction of what the government spends to study other leading causes of death, according to new research in Journal...
Final results from RE-VERSE AD study show that idarucizumab, marketed in the US as Praxbind (Boehringer Ingelheim), was able to immediately reverse the anticoagulant effect of dabigatran etexilate mesylate (Pradaxa, Boehringer Ingelheim) in patients in emergency situations. The effects were...
Chance M Witt and Christopher J McLeod (Rochester, USA) review current treatment of ventricular arrhythmias with cardiac sympathetic denervation.  What is cardiac sympathetic denervation? Most electrophysiologists are fully aware of the complex interplay between the autonomic nervous system and cardiac arrhythmias....
The first participants have been enrolled in Medtronic’s STOP AF First clinical trial. The trial will evaluate the safety and effectiveness of performing pulmonary vein isolation (PVI) with the Arctic Front Advance cryoballoon in patients with symptomatic paroxysmal atrial...
Biotronik’s Evity cardiac resynchronisation therapy pacemaker (CRT-P) has been launched in Japan. It is the company’s highest performing CRT-P, with a battery life of almost 10 years. The device includes a new feature, LV VectorOpt, which is designed to allow...
Cardiologs Technologies SAS has received US Food and Drug Administration (FDA) clearance of its ECG Analysis platform, a cloud-based cardiac monitoring-analysis web service powered by artificial intelligence (AI). Cardiologs’ platform is designed to aid physicians in screening for atrial fibrillation...
The UK’s Information Commissioner’s Office (ICO) has found that the Royal Free National Health Service (NHS) Foundation Trust (London, UK) did not adhere to the UK’s Data Protection Act when it provided patient details to Google DeepMind. The Trust, a...
LifeTech, at the 2017 Congenital and Structural Intervention Congress (CSI; 28 June—1 July, Frankfurt, Germany), announced the launch of a three-year global postmarket surveillance study for the LAmbre left atrial appendage (LAA) closure system. A press release reports that...
A sudden catastrophic loss of heart function, or cardiac arrest, occurred significantly less among adults who acquired health insurance via the Affordable Care Act (ACA), according to new research in Journal of the American Heart Association. In a study of...
Philips and Spectranetics have announced that they have entered into a definitive merger agreement. Pursuant to the agreement, a press release reports, Philips will commence a tender offer to acquire all of the issued and outstanding shares of Spectranetics...
Young adults with a history of asthma are at a greater risk of thickening of the left ventricle according to research published today in JACC: Heart Failure. The prevalence of asthma has been growing during the past decade, occurring in...
The tenth year of data on cardiac arrhythmia treatment is being launched at EHRA EUROPACE - CARDIOSTIM 2017. The edition marks the ten year anniversary of the European Heart Rhythm Association (EHRA) White Book, which reports on the current status...
Breast implants may disrupt an electrocardiogram (ECG) and could result in a false heart attack diagnosis, according to research presented at EHRA EUROPACE - CARDIOSTIM 2017. “Our experience shows that breast implants make it difficult to see the heart with...
A novel smartphone application (app) has been developed that can direct first responders to cardiac arrest victims more than three minutes before the emergency services arrive. Each minute has been shown to increase the chance of survival by 10%. The...
A European network—the European Sudden Cardiac Arrest network (ESCAPE-NET)—has been created to find sudden cardiac arrest causes and compare treatments. In Europe, around 20% of all deaths are caused by sudden cardiac arrest. ESCAPE-NET is backed by the European Heart...
The scientific congresss of the European Heart Rhythm Association (EHRA) is to become an annual event from 2018. The next congress will take place 18–20 March 2018 in Barcelona, Spain. “The yearly EHRA Congress will provide European and worldwide electrophysiologists...
Public Health England (PHE) and the Royal Society for Public Health (RSPH) have published “Everyday Interactions”, a report which aims to support healthcare professionals to record and measure their public health impact.  The report and toolkit were developed in close...
Newly diagnosed asymptomatic atrial fibrillation patients have a higher rate of previous stroke than those with symptoms, according to results from the GLORIA-AF registry presented at EHRA EUROPACE - CARDIOSTIM 2017. The findings highlight the need for screening to...
Breastfeeding may reduce a mother’s risk of having a heart attack or stroke later in life, according to new research published in of the Journal of the American Heart Association. Previous studies have suggested that mothers get short-term health benefits...
New data showing the use of Medtronic’s cardiac resynchronisation therapy (CRT) devices—with its proprietary AdaptivCRT and EffectiveCRT algorithms—to result in lower healthcare system costs and improved therapy delivery in heart failure patients who also have atrial fibrillation (AF), have...
Pacemakers and other cardiac devices can help solve forensic cases, according to a study presented at EHRA EUROPACE - CARDIOSTIM 2017. Devices revealed the time and cause of death in some cases where autopsy failed to do so. “In forensic...
Stereotaxis has announced the European launch of the e-Contact module, designed to provide physicians with a simple-to-interpret indicator of catheter tip-to-tissue contact. The e-Contact module is primarily impedance-based which allows for a direct measurement of the capacity to deliver radiofrequency...
The Sound Doctor, a UK-based provider of health-related film and audio content for patients, has announced a series of 40 films on heart failure. The films, released in partnership with Guy’s and St Thomas’ NHS Foundation Trust and Kings College...
Happitech, Arrhythmia Alliance and Bug Labs are to announce the launch of the Heart for Heart e-health initiative. This programme asks people to participate in the world’s largest crowdsourced heart health initiative by inviting them to contribute their heart...
Medtronic has announced that its Reactive atrial-based antitachycardia pacing (ATP) therapy slows the progression of atrial fibrillation (AF) in patients with implanted cardiac devices. A real-world analysis of nearly 8,800 patients was presented at EHRA EUROPACE-CARDIOSTIM 2017. According to a...
Researchers have designed a safer antiplatelet drug based on a snake venom, according to new research in Arteriosclerosis, Thrombosis and Vascular Biology. Scientists from the National Taiwan University, Taipei City, Taiwan, have designed a drug to interact with the protein...
Highlights: -Could etripamil nasal spray be a “game-changer” for paroxysmal supraventricular tachycardia? -Long detection in single-chamber ICDs decreases mortality and unnecessary shocks -Chance M Witt and Christopher J McLeod: Cardiac sympathetic denervation for treatment of ventricular arrhythmias: Where are we now? -Advertorial: S-ICD...
Highlights: -Could etripamil nasal spray be a "game-changer" for paroxysmal supraventricular tachycardia? -Long detection in single-chamber ICDs decreases mortality and unnecessary shocks -Chance M Witt and Christopher J McLeod: Cardiac sympathetic denervation for treatment of ventricular arrhythmias: Where are we now? -Advertorial: S-ICD...
This video has been sponsored by LivaNova. The RESPOND-CRT clinical trial is a relevant and significant study in the field of cardiac resynchronisation therapy. It has answered an important question finally, that optimisation can work, and that optimisation, if done...
The benefits of the Subcutaneous Implantable Cardioverter Defibrillator (S-ICD, Boston Scientific) over transvenous (TV)-ICD, including lower rates of lead-related complications and lower in-hospital complication rates in some instances, have been demonstrated in three recently published head-to-head studies by Friedman...
It is safe to reimplant a new cardiac device after the removal of an infected one, and repeat infection rates are low, a large multicentre prospective study has shown. The findings also suggest that timing of the reimplantation does...
Biotronik has received CE mark approval for 3 tesla (T) full-body scans with its latest range of magnetic resonance (MR) conditional pacemaker systems, including single- and dual-chamber pacemakers from the Edora/Evity/Enitra series. Biotronik’s ProMRI pacemaker portfolio was previously approved...

Carlos Morillo

Carlos Morillo (Calgary, Canada) was one of the first physicians to document the potential of ablation of the pulmonary vein region as a strategy to treat atrial fibrillation (AF) experimentally. Born in Bogotá, Colombia, Morillo is currently focusing on...
Sex-specific cardiovascular drug dosages are needed to reduce adverse reactions in women, according to a position paper from the European Society of Cardiology (ESC). The paper, published in the European Heart Journal - Cardiovascular Pharmacotherapy, outlines the differences between...
Writing for Cardiac Rhythm News, Jan Steffel (Zurich, Switzerland) reviews current data and practice regarding safety of insertable cardiac monitors (ICMs) implantation in office settings.  ICMs are finding increasingly varied applications—not only in cardiology for the diagnosis of syncope—but also...
The use of a novel implantable string subcutaneous defibrillator (ISSD, Newpace) that has no can, and has been designed to be placed without the need for a surgical pocket, may allow improved patient compliance and aesthetics, is less invasive,...
A phase 2 trial (NODE-1) of a nasal spray formulation of etripamil (Milestone Pharmaceuticals) shows it is safe and effective at terminating paroxysmal supraventricular tachycardia (PSVT) and has the potential to be a “game-changer” in the treatment of the...
Biotronik has announced the availability of the Edora line of devices, the company's first available pacemaker series featuring the company's magnetic resonance imaging (MRI) AutoDetect technology. Edora SR-T is the smallest MR-conditional pacemaker with automated MRI detection capability available in...
Highlights: - Uninterrupted dabigatran outperforms warfarin in atrial fibrillation ablation - Martin Burke: Artificial intelligence - Roberto Keegan: The new LAHRS - Transvenous lead extraction is a safe procedure with low complication rates - In memoriam: Mark E Josephson - Thomas Deering: Profile https://o6xux43a6gs4eidym2svvhon-wpengine.netdna-ssl.com/wp-content/uploads/sites/12/2017/06/36-Cardiac-Rhythm-News_low-res-EU.pdf
Highlights: - Uninterrupted dabigatran outperforms warfarin in atrial fibrillation ablation - Martin Burke: Artificial intelligence - Roberto Keegan: The new LAHRS - Transvenous lead extraction is a safe procedure with low complication rates - In memoriam: Mark E Josephson - Thomas Deering: Profile     https://o6xux43a6gs4eidym2svvhon-wpengine.netdna-ssl.com/wp-content/uploads/sites/12/2017/06/36-Cardiac-Rhythm-News_low-res-US.pdf
This video has been sponsored by LivaNova. Over the past two decades there have been several optimisation strategies, whether they are echo-guided or EKG-guided, aimed to improve outcomes in cardiac resynchronisation therapy (CRT) patients. However, none of them have worked...
Left atrial appendage closure with the Watchman device (Boston Scientific) is safe and effective at stroke prevention, with a high implant and sealing success, even in patients that are contraindicated to and not using oral anticoagulants, one-year follow-up of...
Two case reports—from Michael Kwasman, cardiac electrophysiologist, Providence Sacred Heart Medical Center, Spokane, USA, and Rakesh Latchamsetty, cardiac electrophysiologist, University of Michigan Health Center, Ann Arbor, USA—demonstrate the potential of Abbott's EnSite Precision™ Cardiac Mapping System. https://o6xux43a6gs4eidym2svvhon-wpengine.netdna-ssl.com/wp-content/uploads/sites/12/2017/05/CRN-36_Abbott-Case-Reports.pdf
Men seem to have worse chemotherapy-induced cardiomyopathy than women despite receiving similar cancer treatments, according to research presented at EuroCMR 2017. “Cancer patients are living longer because of improved treatment but the side effects of treatment include cardiovascular morbidity and...
Patients who suffer superior vena cava tears (SVC) during lead extraction are more likely to survive when treatment includes an endovascular occlusion balloon, a late-breaking trial study presented at the Heart Rhythm Society’s 38th Annual Scientific Sessions (10‒13 May,...
Initial real-world experience with the S-ICD (subcutaneous implantable cardioverter defibrillator) in the USA show that implant success rate is high and short-term complications acceptably low. Michael R Gold, of the Medical University of South Carolina, Charleston, USA, presented the findings...
Unnecessary shocks and all-cause mortality are reduced in patients treated with a single chamber implantable cardioverter defibrillator (ICD) programmed with a long detection window. Lead investigator Maurizio Gasparini (Humanitas Research Hospital, Rozzano-Milano, Italy) presented the findings from the ADVANCEIII trial...
New data supporting the clinical performance of the company's exclusive EffectivCRT diagnostic and AdaptivCRT algorithm in heart failure patients who receive cardiac resynchronisation therapy (CRT) devices have been presented at Heart Rhythm 2017, the Heart Rhythm Society's 38th Annual...
Postmenopausal women who reached menopause at an earlier age or who never gave birth are at a higher risk for heart failure, according to research published today in the Journal of the American College of Cardiology. Previous research has found...
Many patients with an irregular heartbeat, known as atrial fibrillation, are not receiving recommended blood thinning medication they need to prevent strokes, according to a study published today in the Journal of the American College of Cardiology. People who have...
A substantial number of patients at risk for atrial fibrillation (AF) may remain undetected using conventional monitoring techniques, a late-breaking clinical trial session at the Heart Rhythm Society’s 38th Annual Scientific Sessions (10‒13 May, Chicago, USA) heard. Investigators for...
The Micra leadless pacemaker continues to demonstrate a high implant success rate and a low level of major complications at 30 days in a real world setting, and in the hands of operators with no prior experience in Micra...
Siemens Healthineers is joining forces with Imricor Medical Systems to develop an integrated system that combines the clinical benefits of real-time magnetic resonance imaging (MRI) scans with 3D-guided cardiac ablation. The companies’ goal is the development of MRI-compatible devices that...
Medtronic has received US Food and Drug Administration (FDA) approval for a portfolio of quadripolar cardiac resynchronization therapy-pacemakers (CRT-Ps) that are designed to improve therapy delivery for patients with heart failure. These devices also allow patients to receive magnetic...
When patients with heart failure were re-hospitalised within a month, those who returned to the same hospital were discharged quicker and were more likely to survive, according to new Canadian research in the Journal of the American Heart Association. In...
The first three persistent atrial fibrillation patients have been treated using Adagio’s cryolinear ablation technology. This follows the successful treatment of over 25 arrhythmia patients in the company's CryoCure clinical trial. The Adagio cryolinear ablation technology is designed to enable...
Abbott has announced CE mark and first use of the new Confirm Rx ICM. According to a company release, this is the world’s first smartphone compatible ICM that will help physicians identify difficult to detect cardiac arrhythmias, including atrial fibrillation...
The US Food and Drug Administration (FDA) has approved Boston Scientific’s Resonate family of implantable cardioverter defibrillator (ICD) and cardiac resynchronisation therapy defibrillator (CRT-D) systems. The approval includes new features in the Resonate devices including SmartCRT technology with Multisite Pacing...
Biotronik has announced US Food and Drug Administration (FDA) approval of the company's MultiPole pacing (MPP) technology, designed to provide physicians with additional treatment options for heart failure patients who have been non-responsive to cardiac resynchronisation therapy (CRT). MPP...
Biotronik has announced the availability of the first US Food and Drug Administration (FDA)-approved cardiac rhythm management (CRM) devices with technology that automatically recognises when a patient enters a magnetic resonance imaging (MRI) environment. The company’s MRI AutoDetect technology is...
The US Food and Drug Administration (FDA) has approved Biotronik’s Sentus ProMRI, the thinnest quadripolar left ventricular lead available in the country. Sentus ProMRI is approved for use with heart failure devices based on data collected during the QP ExCELs...
Remote monitoring of implantable cardioverter defibrillators (ICD), particularly in cardiac resynchronisation therapy (CRT-D), reduces direct healthcare costs compared with standard monitoring, an economic evaluation of the results of the EFFECT trial has found. The EFFECT study was a multicentre observational...
Early post-procedural mortality occurred in 5% of cases of radiofrequency catheter ablation in patients with scar-related ventricular tachycardia (VT), with more than half of the events occurring in hospital, a trial of a contemporary cohort of patients has found. The...
Boston Scientific has announced the schedule of key data presentations, including two late-breaking clinical trials that will be featured at the Heart Rhythm Society’s 38th Annual Scientific Sessions (10‒12 May, Chicago, USA). Notably, the post-market approval data collected on the...
Surgical left atrial appendage occlusion (LAAO) is associated with a reduction of thromboembolism and all-cause mortality among older atrial fibrillation (AF) patients undergoing cardiac surgery, according to an observational study in the USA. The results were presented in a...
Acutus Medical has announced the FDA clearance of the AcQGuide Steerable Sheath, which marks the first US regulatory milestone for the company. The AcQGuide Steerable Sheath is a percutaneous catheter introducer designed to provide additional maneuverability to catheters that are...

Thomas F Deering

Thomas F Deering (Piedmont Heart Institute, Atlanta, USA) considers that the biggest challenge in electrophysiology (EP) is to “move from the volume to the value world of healthcare delivery” finding ways to improve lives in a “quality and cost-efficient...
Teleflex has announced 510(k) clearance from the US Food and Drug Administration (FDA) for its AC3 Optimus Intra-Aortic Balloon Pump (IABP).This device helps a weakened heart pump blood and can deliver IABP therapy to a broad range of patients, even...
Unemployment is associated with a 50% higher risk of death in patients with heart failure, according to research presented at Heart Failure 2017 and the 4th World Congress on Acute Heart Failure.1 The observational study in more than 20...
Death in patients with heart failure is inversely related to the wealth of the country they live in, according to late breaking results from the INTERCHF study presented at Heart Failure 2017 and the 4th World Congress on Acute...
A new AF atrial fibrillation (AF) patient survey carried out by the AF Association has been launched. Results showed that 79% of patients surveyed—who are currently on a vitamin K antagonist such as warfarin—said that they would favour the...
Physical activity can lower the risk of heart damage in middle-aged and older adults and reduce the levels of heart damage in people who are obese, according to research published today in JACC: Heart Failure. Obesity is associated with structural...
Mark E Josephson, a pioneer of clinical cardiac electrophysiology (EP), passed away at the age of 73 on 11 January 2017 after a courageous battle with cancer. With his passing, the EP community lost a great physician whose achievements...